@ 16:33hrs Shepherds & Engine 4 were alerted to a reported MVA with injuries one vehicle into a tree around the 100 block of Rankinhill Rd. ECOM advised units they received a call reporting two patients still inside the vehicle. Minutes later Engine 4 along with Rescue 5 arrived on location and confirmed a pickup head on into a tree, command established (E4) out investigating. Moments later command (Capt Conrad) advised of one confirmed pin-in (driver) & one entrapment (passenger). Personnel from both agencies worked together by cribbing & stabilizing same before any extrication commenced. Once the vehicle was stable personnel had to take extreme caution on how the extrication was done as both pt's were severely injured. Charlotte's Med-Center Air was contacted and per the request of EMS on location 2 birds were needed. Shepherds Chief 500 (Robinson) and Shepherds Engine 1 were enroute to the LZ location. Within 10 minutes both parties had been extricated and were being attended to by EMS & fire personnel. Once packaged both pt's were enroute to the LZ and loaded for transport to Charlotte. All units were assignment complete back in normal service within 35 minutes. Shepherds would like to thank all responding agencies and personnel on location for their efforts and would like to extend it's deepest sympathies to the families involved.